RuBisCO
A very old enzyme. Still fixing inorganic carbon in the biosphere through yet another mass extinction. Still grabbing the wrong molecule on occasion. Anyway, here are some more phosphoglycerates.
Kill your lawn, grow a garden. As you do this, look within and do the same.
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9·6 months agoYou mean Last Week Tonight? The Late Show is Colbert.
Yay! Cheers! Always happy to help with a Mol Bio question.
Does this help?
https://www.youtube.com/watch?v=8wAwLwJAGHs
Khan Academy - Transcription, Translation, Protein Synthesis (11min)I agree, the article could be written more clearly. Every time I read “DNA letters” I winced.
This part is what stuck with me:
The team also asked Evo to generate a DNA sequence similar in length to some bacterial genomes and compared the results to natural genomes. The designer genome contained some essential genes for cell survival, but with myriad unnatural characteristics preventing it from being functional. This suggests the AI can only make a “blurry image” of a genome, one that contains key elements, but lacks finer-grained details, wrote the team. Like other LLMs, Evo sometimes “hallucinates,” spewing CRISPR systems with no chance of working.
I think what they are trying to say here is DNA can code for mRNA (which is then translated into polypeptides) or it can code for regulation (transcription start sites, inhibitor binding sites, etc).
There’s more to it than just those two, but you get the idea, right?
1·2 years agoLooking very Shane today.
There was a bit of a drought, but it rained again.
https://www.youtube.com/watch?v=Ss_V8V38aHQ